She is best known for her portrayal of Diane Chambers on the sitcom Cheers, for which she received five Emmy nominations, winning in 1983 for Outstanding Lead Actress in a Comedy Series.
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Born Shelley Lee Long on August 23, 1949 in Fort Wayne, Indiana, to parents Ivadine and Leland Long, she was active on her high school speech team, competing in the Indiana High School Forensic Association.